Wellness Education
Renew
Growth hormone naturally declines ~14% per decade after age 30. GH secretagogues and GHRH analogues stimulate the pituitary to release GH in natural pulses — supporting lean mass, fat metabolism, recovery, and anti-aging.
14%
Decline in GH secretion per decade after age 30
~20%
Reduction in visceral fat with Tesamorelin
2x
IGF-1 elevation with combined GHRH + GHRP protocols
How They Work
GHRH analogues (Sermorelin, Tesamorelin, CJC-1295) bind pituitary receptors to trigger GH release. GHRPs (Ipamorelin) amplify those pulses via ghrelin receptors. Recombinant HGH directly provides somatotropin.
Key Benefits
Lean Muscle
GH stimulates IGF-1 production, driving protein synthesis
Fat Metabolism
Increases lipolysis, particularly visceral fat
Recovery
Accelerates tissue repair and exercise recovery
Anti-Aging
Improves sleep, skin elasticity, bone density
Renew Category
5 compounds in this category
Browse all compounds →Educational Content. Category content is for informational purposes only. Not intended as medical advice, diagnosis, or treatment.
Compounds in Renew
5 compoundsSermorelin Acetate
GHRH(1-29) Analogue
- Stimulates natural, pulsatile GH release — not suppressive
- Improves sleep, body composition, and skin within 3-6 months
Reference Codes
[SMO10]10mgIpamorelin
Clean GH Secretagogue
- Selective GH release with no cortisol or prolactin elevation
- Ideal for stacking with GHRH analogues for synergistic pulses
Reference Codes
[IP10]10mgTesamorelin
FDA-Referenced GHRH Analogue
- Clinically proven ~20% reduction in visceral adipose tissue
- Improves IGF-1 levels, lipid profiles, and cognitive function
Reference Codes
[TSM10]10mgHGH
Recombinant Somatotropin
- Direct GH replacement for muscle, fat, and regeneration
- Supports cellular regeneration, IGF-1 production, recovery
Reference Codes
[H24]24iuEpitalon (Epithalon)
Telomerase Activator Tetrapeptide
- Backed by over two decades of research from the St. Petersburg Institute of Bioregulation
- One of the few compounds shown to activate telomerase in human somatic cells
Reference Codes
[ET10]10mg[ET50]50mgResearch in Renew
Epitalon: Telomerase Activation and the Science of Biological Aging
Epitalon activates telomerase to maintain telomere length — what decades of research show, where the gaps are, and why longevity researchers watch.
March 15, 2026 · 13 min read
Understanding Your Growth Hormone System
How the growth hormone axis works — pituitary signaling, GHRH, ghrelin receptors, and IGF-1 explained. Why GH declines 14% per decade and what that means.
November 22, 2025 · 11 min read
Sermorelin vs. HGH: What the Research Actually Compares
The pulsatile physiology of Sermorelin against direct HGH replacement — clinical differences, feedback loops, and what the evidence says about each approach.
November 5, 2025 · 10 min read
What Are Peptides? A Science-First Primer
Amino acid chains, receptor signaling, and why peptides are among the most studied compound classes in modern biochemistry — explained clearly.
August 12, 2025 · 7 min read
All compound profiles are for educational reference only. This content does not constitute medical advice, diagnosis, or treatment recommendations. Consult a qualified healthcare provider.